Skip to main content

Bulfield, Grahame, 1941-: (geneticist, formerly director and chief executive, Roslin Institute, Edinburgh and vice-principal, University of Edinburgh)

 Person

Dates

  • Existence: 1941-:

Biography

Grahame Bulfield was born in Leeds in 1941, and attended school in Cheshire, where he developed an interest in agriculture and farming. In 1959 he began at the University of Leeds, reading for a BSc in Agriculture with Honours in animal production. He became interested in genetics and completed his honours project on the subject of 'Beef Sire Performance and Progeny Testing.'

After a lecturer recommended the Institute of Animal Genetics in Edinburgh, Bulfield began studying for a Diploma in Animal Genetics at the Institute in 1964, with a scholarship from the Ministry of Agriculture. After a spell at the University of Uppsala, Sweden, as a Yorkshire Agricultural Society Travelling Fellow, Bulfield began studying for a PhD in Genetics at the University of Edinburgh, with a studentship from the Agricultural Research Council. His thesis was on the biochemical genetics of two obese mutants in the mouse, and his supervisors were C.H. Waddington, D.S. Falconer, H. Kacser and G.S. Boyd.

Between 1968 and 1970, Bulfield worked in the Department of Genetics, University of California, as a Fulbright Fellow. He returned to Edinburgh in 1971 to work with Henrik Kacser on two MRC-funded projects on the screening and analysis of mouse mutants of human inherited disease.

In 1976, Bulfield was appointed Lecturer and Medical Convenor of Medical Genetics at the University of Leicester, where his research included mouse disease mutants, the genetic control of gene expression and the genetics of growth. Here Bulfield made the significant discovery of a mutation on the mouse X-chromosome which is still used as an animal model for understanding Duchenne and Becker muscular dystrophy in humans.

Bulfield returned to Edinburgh in 1981 as Head of the Genetics Group at the Poultry Research Centre. In 1986, part of the PRC became integrated into the newly-formed Edinburgh Research Station of the Institute of Animal Physiology and Genetics Research (IAPGR), and Bulfield was appointed Head of the Gene Expression group. In 1988 he became head of the entire Station. When the IAPGR-ERS became independent from its sister institute in Cambridge, and renamed Roslin Institute, Bulfield became director and Chief Executive. Bulfield steered Roslin through a time of scientific innovation, the growth of various spin-out biotechnology companies, government scrutiny of research establishments, as well as unprecedented public and media attention, particularly surrounding the Institute's work on cloned and transgenic animals, including Dolly the sheep (b.1996). In 1997, Bulfield and colleagues appeared before the House of Commons Select Committee on Science and Technology to answer questions on cloning.

In 2002, Bulfield retired as Roslin's director and moved over to the University of Edinburgh to become Vice-Principal and Head of the College of Science and Engineering. He is currently Emeritus Professor of Genetics at the University of Edinburgh.

Grahame Bulfield has served on a wide range of government and public committees and Working Parties. He has been a non-executive director of nine companies and an advisor and consultant to both a US and UK biotechnology venture capital fund as well as a UK biotechnology company. Bulfield was appointed an Honorary Professor of the University of Edinburgh in 1990, to a Personal Chair of Animal Genetics in 2002 and elected to a Fellowship of the Royal Society of Edinburgh in 1992. In 1999 he was appointed Honorary Fellow of the Royal Agricultural Society of England. He was awarded a CBE for services to Animal Genetics in 2001.

Found in 104 Collections and/or Records:

Collection of documents relating to student theatre in Edinburgh gathered together by Grahame Bulfield

 Fonds — Box CLX-A-375
Identifier: Coll-1892
Scope and Contents This collection consists of 67 physical items, mainly theatre programmes, hand-outs, and newspaper cuttings relating to student theatre in Edinburgh in the late 1960s. Also includes an inventory, and a list of known student performances in Edinburgh from autumn 1964 to summer 1972. Most items are originals, but a few are copies.Click ...
Dates: late 1960s

Correspondence between Grahame Bulfield and Ray Baker, 2000

 File
Identifier: EUA IN23/4/4/5/1/5
Scope and Contents From the Sub-Fonds:

Comprises records of Roslin Institute which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. The majority of these records originate from the office of the Institute Secretary, with a number from the Director and Assistant Director. In the latter cases this is noted in the catalogue.

Dates: 2000

Detection of quantitative trait loci from frequency changes of marker alleles under selection, 1993

 Item
Identifier: Coll-1362/4/125
Scope and Contents

Located in Roslin Institute Staff Papers 1993. Part 1.

Dates: 1993

Director's copies of draft minutes of the General Purposes Committee, 1996-2002

 File
Identifier: EUA IN23/4/1/11
Scope and Contents From the Sub-Fonds:

Comprises records of Roslin Institute which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. The majority of these records originate from the office of the Institute Secretary, with a number from the Director and Assistant Director. In the latter cases this is noted in the catalogue.

Dates: 1996-2002

Director's copies of Senior Staff Meeting minutes, 04 July 1986-07 December 1989

 File
Identifier: EUA IN23/3/1/5/1
Scope and Contents From the Sub-Fonds:

Comprises records of IAPGR-ERS which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. Most of the files are from the Secretary's office, although there are some from the Head of Station and individual scientists.

Dates: 04 July 1986-07 December 1989

Director's draft overview of Roslin Institute for the 1997 Visiting Group, 1997

 File
Identifier: EUA IN23/4/1/2/1/6
Scope and Contents

Contains two annotated reports: 'Roslin Institute: Technology Interaction Policies and Achievements 1992-1996' and 'Director's Overview.' Grahame Bulfield's files. Original file titled 'Institute Assessment Exercise: 1997 VG - Director's Overview Statement and Knowledge Transfer.'

Dates: 1997

Director's draft response to PMS Review of Institutes' Commercial Units, 1994

 File
Identifier: EUA IN23/4/1/2/3/1
Scope and Contents From the Sub-Fonds:

Comprises records of Roslin Institute which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. The majority of these records originate from the office of the Institute Secretary, with a number from the Director and Assistant Director. In the latter cases this is noted in the catalogue.

Dates: 1994

Director's file concerning Roslin Institute's 1998/1999 Business Plan, May-June 1998

 File
Identifier: EUA IN23/4/1/3/1/4
Scope and Contents From the Sub-Fonds:

Comprises records of Roslin Institute which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. The majority of these records originate from the office of the Institute Secretary, with a number from the Director and Assistant Director. In the latter cases this is noted in the catalogue.

Dates: May-June 1998

Director's file concerning Roslin Institute's 1999/2000 Business Plan, 1999

 File
Identifier: EUA IN23/4/1/3/1/6
Scope and Contents From the Sub-Fonds:

Comprises records of Roslin Institute which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. The majority of these records originate from the office of the Institute Secretary, with a number from the Director and Assistant Director. In the latter cases this is noted in the catalogue.

Dates: 1999

Additional filters:

Type
Archival Object 102
Collection 2
 
Subject
Animal Genetics 59
Mice 31
Poultry 12
Transgenic animals 8
Enzymes 6