This brown leather notebook covers Lyell's activity from Ishcia to Naples. It contains geological notes on Herculaneum, Pompeii, Versuvius; Notes on William Hamilton on great earthquakes in Calabria in 1782; 'Differences between geologist and ordinary observer'; 'Partial activity in the agents of change'; 'Migration'. The front cover plate reads "No 5 Italy 1828 Ischia to Naples Oct 31st to Nov. 15th."

The following table of contents is Lyell's own words, copied from Lyell's own "Index", found at the beginning and end of the notebook, transcribed from digital surrogates using the platform Transkribus. When known, Lyell's abbreviations and contractions have been expanded using brackets []. When writing is unclear, and transcription is not possible, this is denoted using [...]. Quotation marks are Lyell's own notation for ditto, as is the abbreviation "d'o". The inclusion of [sic] indicates the misspelling of a word is deliberate and taken from the notebook.

p. 3, Hamilton on Calabria
p. 13, Ischia
p. 17, Pompeii (things found out)
p. 22, Elsa basin (fossils)
p. 30, Sienna basin (fossils)
p. 33, Vesuvius
p. 34, Torre del Greco
p. 32, Naples
p. 52, Castella-mare
p. 56, Salita della Cava
p. 62, Eboli to Pestum
p. 68, Salerno
p. 68,74,130, Pompeii
p. 72, [Pompeii] Temple of Hercules
p. 94, Portici, Vesuvius
p. 107, Arco del Cavallo
p. 111, Temple of Serapis
p. 114, Nisita
p. 118, Temple of Serapis
p. 124, Puzzuoli
p. 130, Herculaneum
p. 132, M. Barbaro
p. 136, 142, Monte Nuovo
p. 136, Baths of Nero
p. 140, Cumean Sybils Cave
p. 144, Coast of bay of Naples