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Embryonic Stem Cells

 Subject
Subject Source: Medical Subject Headings
Scope Note: Cells derived from the blastocyst inner cell mass which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.

Found in 9 Collections and/or Records:

Copy of a grant application to the Motor Neurone Disease Association for the proposed project 'Deriving motor neurones and astroglia from human embryonic stem cells: exploring models, mechanisms and the potential for transplantation', 2003

 File — Box CLX-A-1497: Series Coll-1320/2, Box: data_value_missing_46a6b4ebd03faa99476ca6a5c4586881, Box: data_value_missing_b3f2ac1d2289bb0b3c7cf8af773a2195
Identifier: Coll-1320/2/2/19
Scope and Contents From the Sub-Series: Contains copies of draft and completed grant application forms for various scientific projects, with related papers, including correspondence and reports to funding bodies. Proposed projects include research on stem cells, cloning, transgenics and animal embryology.
Dates: 2003

Correspondence between Ian Wilmut and various companies regarding potential collaborations on human embryonic stem cell research, 1998

 File
Identifier: EUA IN23/4/8/2/6
Scope and Contents From the Sub-Fonds: Comprises records of Roslin Institute which relate to governance, administration, finance, legal, estates, human resources, external relations, events and publicity. Also contains some research data. The majority of these records originate from the office of the Institute Secretary, with a number from the Director and Assistant Director. In the latter cases this is noted in the catalogue.
Dates: 1998

File concerning a grant application to the Agricultural and Food Research Council for the project 'Early transcription events during ES cell differentiation', November 1987-April 1992

 File — Box CLX-A-1494: Series Coll-1320/2, Box: data_value_missing_96533e11ea8d1c358d017ce425319c01, Box: data_value_missing_1f2e02aebc4246526a2102657246fedf
Identifier: Coll-1320/2/2/1
Scope and Contents Contains: photocopies of grant applications and related correspondence; Ian Wilmut's handwritten notes from discussions and meetings, reprints of scientific papers, photographs of cells taken through a microscope and a copy of reports from the AFRC Stem Cell Molecular Biology workshop (5-7 April 1992).
Dates: November 1987-April 1992

File regarding the application for HFEA license R0158-1-a for the project 'Derivation of human embryo stem cells by cell nuclear replacement technology development and the study of Motor Neuron disease', 2004-2005

 File — Box CLX-A-1501: Series Coll-1320/2, Box: data_value_missing_7f052e8ef38e306c3aea1287509fa75d, Box: data_value_missing_ccc921af981a8bf28350e9fba593b2d1
Identifier: Coll-1320/2/5/3
Scope and Contents Contains a copy of the application form and related correspondence, and a copy of the report of the inspection visit by the HFEA to Roslin Institute's Department of Gene Expression and Development on 2 November 2004.
Dates: 2004-2005

File relating to a grant application to the Agricultural and Food Research Council for the project 'Factors that increase the efficiency of embryonic stem cell isolation', October 1991-August 1994

 File — Box CLX-A-1495: Series Coll-1320/2, Box: data_value_missing_87e81f2125de6c82d65c68b8b1a22ccc, Box: data_value_missing_80a43d56758ce1a4988783b9af471219
Identifier: Coll-1320/2/2/4
Scope and Contents Contains copies of draft grant application forms, referees' comments and related correspondence; Ian Wilmut's handwritten notes from discussions and meetings; papers concerning the AFRC Trangenic Animals Programme research review meeting (25-27 March 1991) and a copy of the proposed new UK patent application for 'TNT Cells for Nuclear Transfer' (August 1994). Also contains application forms and correspondence relating to 'Cell cycle and commitment in mammalian embryos' and 'Transcriptional...
Dates: October 1991-August 1994

File relating to a grant application to the Agricultural and Food Research Council for the project 'Study of the early embryonic development of farm animals and its application to the isolation of embryonal stem cell lines', January 1991-February 1992

 File — Box CLX-A-1495: Series Coll-1320/2, Box: data_value_missing_e63469c4bb32cebc300ced3a2c07ef0d, Box: data_value_missing_598e4273176e2e1cb8b865935b21407b
Identifier: Coll-1320/2/2/3
Scope and Contents From the Sub-Series: Contains copies of draft and completed grant application forms for various scientific projects, with related papers, including correspondence and reports to funding bodies. Proposed projects include research on stem cells, cloning, transgenics and animal embryology.
Dates: January 1991-February 1992

File relating to the project 'Cloning of transgenic mice and rats by nuclear transfer with somatic and embryonic stem cells', 2001-2004

 File — Box CLX-A-1496: Series Coll-1320/2, Box: data_value_missing_2e14dc2e0f496288579b2766404b0230, Box: data_value_missing_596d27f097e24b10c9dd565f24818d87
Identifier: Coll-1320/2/2/14
Scope and Contents From the Sub-Series: Contains copies of draft and completed grant application forms for various scientific projects, with related papers, including correspondence and reports to funding bodies. Proposed projects include research on stem cells, cloning, transgenics and animal embryology.
Dates: 2001-2004

File relating to the project 'Nanog in pig early development and ES cell isolation', 2004-2005

 File — Box CLX-A-1497: Series Coll-1320/2, Box: data_value_missing_11ebd1a4e728dd18af8b88a8bfa812ac, Box: data_value_missing_a230c0c52ecaee813bce827b472f403d
Identifier: Coll-1320/2/2/22
Scope and Contents Contains application for for a National Institutes of Health Department of Health and Human Services grant and related project costings.
Dates: 2004-2005

Files relating to the HFEA licenses R0136 for the projects 'Platform technologies underpinning human embryonic stem cell derivation' and 'Derivation of research and therapeutic grade human embryonic stem cells', 2001-2007

 File — Multiple Containers
Identifier: Coll-1320/2/5/2
Scope and Contents Files 1-2 (2001-2004) contain: papers concerning HFEA license for the project 'Platform technologies underpinning human embryonic stem cell derivation' at Roslin Institute under Paul De Sousa and Ian Wilmut, including a copy of the license and correspondence with the HFEA and collaborators in other institutions; correspondence with the HFEA about their pilots for Alerts and for patient information and consent forms for donating gametes or embryos for research; a copy of the HFEA Licensed...
Dates: 2001-2007