An index at the beginning of this substantial volume of clinical case notes lists 28 women and 31 men with their symptoms and treatment recorded in manuscript notes over more than 600 pages. The manuscript offers much information on the methods of these two leading 18th century Scottish physicians.

Three bound volumes of notes of lectures 'on the practice of physic', given by James Gregory (1753-1821), Professor of Medicine at the University of Edinburgh. The volumes have a bookplate with the letters 'RB'.