Amyotrophic Lateral Sclerosis
Subject
Subject Source: Medical Subject Headings
Scope Note: Notes = A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. ,Created For = LHSA-Dott
Found in 41 Collections and/or Records:
PR2.20354, 1959-1964
Item
Identifier: LHB1 CC/24/PR2.20354
Scope and Contents
Correspondence, tracer card, reports, typed case summary, charts and notes relating to male patient from Scotland (outside Edinburgh and the Lothians) aged 29 at first examination in 1959. Conditions mentioned include: degenerative amyotrophic lateral sclerosis; weakness and wasting of legs; and calf pain. No treatment given. Patient discharged.
Dates:
1959-1964