Malformations of Cortical Development
Subject
Subject Source: Medical Subject Headings
Scope Note: Notes = Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal CELL PROLIFERATION or APOPTOSIS; abnormal neuronal migration; and abnormal establishment of cortical organization via neurite extension, synaptogenesis, or neuronal maturation. As well as mutations effecting these developmental processes directly, there are a variety of inborn metabolic errors, such as PEROXISOMAL DISORDERS and mitochondrial and pyruvate metabolic disorders which effect them secondarily and also exhibit these malformations. They are common causes of EPILEPSY and developmental delay and are often a component of multiple congenital anomalies.,Created For = LHSA-Dott
Found in 1 Collection or Record:
PR1.703, 1933-1934
Item
Identifier: LHB1 CC/20/PR1.703
Scope and Contents
Typed case summary, drawing and charts relating to male patient from Scotland (outside Edinburgh and the Lothians) aged 47 at first examination in 1933. Conditions mentioned include: diplopia; headache; epilepsy; seizures; and cortical atrophy. Surgical treatment given. Patient discharged.
Dates:
1933-1934