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Optic Atrophy, Hereditary, Leber

 Subject
Subject Source: Medical Subject Headings
Scope Note: Notes = A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. ,Created For = LHSA-Dott

Found in 4 Collections and/or Records:

PR2.164, 1941

 Item
Identifier: LHB1 CC/24/PR2.164
Scope and Contents

Typed case summary, charts and correspondence relating to male from Edinburgh and the Lothians aged 45 at first examination in 1941. Conditions mentioned include: failure of vision; and Leber's optic atrophy. No treatment given. Patient discharged.

Dates: 1941

PR2.741, 1942

 Item
Identifier: LHB1 CC/24/PR2.741
Scope and Contents

Typed case summary and correspondence relating to male from Scotland (outside Edinburgh and the Lothians) aged 46 at first examination in 1942. Conditions mentioned include: failure of vision; and Leber's disease. No treatment given. Patient discharged.

Dates: 1942

PR4.2441, 1933

 Item
Identifier: LHB1 CC/22/PR4.2441
Scope and Contents

Typed case summary, charts and correspondence relating to male from Scotland (outside Edinburgh and the Lothians) aged 43 at first examination in 1933. Conditions mentioned include: Leber's disease; central scotoma; dizziness; and headache. No treatment given. Patient discharged.

Dates: 1933

PR4.2444, 1933-1942

 Item
Identifier: LHB1 CC/22/PR4.2444
Scope and Contents

Typed case summary, charts, notes and correspondence relating to male from Scotland (outside Edinburgh and the Lothians) aged 33 at first examination in 1933. Conditions mentioned include: disseminated sclerosis; Leber's disease; centrocaecal scotoma; and vision impairment. No treatment given. Patient discharged.

Dates: 1933-1942