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Prions

 Subject
Subject Source: Medical Subject Headings
Scope Note: Notes = Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc ( PRPSC PROTEINS) and the cellular isoform PrPC ( PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.,Created For = TD

Found in 1 Collection or Record:

Polymorphism analysis of the prion gene in BSE-affected and unaffected cattle, 1994

 Item
Identifier: Coll-1362/4/560
Scope and Contents

Located in Roslin Institute Staff Papers 1994. Part 2.

Dates: 1994