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Tuberous Sclerosis

 Subject
Subject Source: Medical Subject Headings
Scope Note: Notes = Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.,Created For = LHSA-Dott

Found in 31 Collections and/or Records:

PR4.665, 1933

 Item
Identifier: LHB1 CC/22/PR4.665
Scope and Contents

Correspondence relating to female patient from Edinburgh and the Lothians aged 12 at first examination in 1933. Conditions mentioned include: encephalitis; paralysis; convulsive seizures; and cerebral sclerosis. No treatment given. Patient discharged.

Dates: 1933

PR4.709, 1934

 Item
Identifier: LHB1 CC/22/PR4.709
Scope and Contents

Typed case summary, correspondence and notes relating to male patient from Scotland (outside Edinburgh and the Lothians) aged 22 at first examination in 1934. Conditions mentioned include: epilepsy; cerebral thrombosis; pneumonia; and cerebral sclerosis. No treatment given. Patient discharged.

Dates: 1934

PR4.714, 1934-1947

 Item
Identifier: LHB1 CC/22/PR4.714
Scope and Contents

Correspondence, typed case summary, reports, charts and notes relating to female from Scotland (outside Edinburgh and the Lothians) aged 25 at first examination in 1934. Conditions mentioned include: epilepsy; and cortical sclerosis. Nonsurgical treatment given. Patient discharged.

Dates: 1934-1947

PR4.728, 1934-1936

 Item
Identifier: LHB1 CC/22/PR4.728
Scope and Contents

Notes and correspondence relating to female patient from Scotland (outside Edinburgh and the Lothians) aged 20 at first examination in 1934. Conditions mentioned include: concussional head injury; epilepsy; depression; and diffuse cortical sclerosis. No treatment given. Patient discharged.

Dates: 1934-1936

PR4.837, 1935-1937

 Item
Identifier: LHB1 CC/22/PR4.837
Scope and Contents

Typed case summary and correspondence relating to female from Scotland (outside Edinburgh and the Lothians) aged 24 at first examination in 1935. Conditions mentioned include: cortical sclerosis; head injury; headache; and epilepsy. No treatment given. Patient discharged.

Dates: 1935-1937

PR4.892, 1936

 Item
Identifier: LHB1 CC/22/PR4.892
Scope and Contents

Typed case summary, notes and correspondence relating to female from Edinburgh and the Lothians aged 36 at first examination in 1936. Conditions mentioned include: ?encephalitis; cerebral sclerosis; obesity; and epilepsy. No treatment given. Patient discharged.

Dates: 1936

PR2.5654, 1947

 Item
Identifier: LHB1 CC/24/PR2.5654
Scope and Contents

Typed case summary, reports, notes, autopsy report, photographs and correspondence relating to male patient from Edinburgh and the Lothians aged 16 at first examination in 1947. Conditions mentioned include: spongioblastoma; epilepsy; tuberose sclerosis; papilledema; and adenoma sebaceum. Surgical and nonsurgical treatment given. Patient died in hospital.

Dates: 1947

PR2.8124, 1949-1950

 Item
Identifier: LHB1 CC/24/PR2.8124
Scope and Contents

Typed case summary, report and correspondence relating to female patient from Edinburgh and the Lothians aged 50 at first examination in 1949. Conditions mentioned include: headache; unconsciousness; epilepsy; and tuberose sclerosis. No treatment given. Patient discharged.

Dates: 1949-1950

PR4.1269, 1938

 Item
Identifier: LHB1 CC/22/PR4.1269
Scope and Contents

Typed case summary and correspondence relating to female patient from Great Britain (excluding Scotland) aged 5 at first examination in 1938. Conditions mentioned include: ?tuberous sclerosis; optic atrophy; spasticity in right limbs; and epilepsy. No treatment given. Patient discharged.

Dates: 1938

PR4.1294, 1938

 Item
Identifier: LHB1 CC/22/PR4.1294
Scope and Contents

Notes and correspondence relating to male patient from Scotland (outside Edinburgh and the Lothians) aged 3 at first examination in 1938. Conditions mentioned include: congenital cerebral sclerosis; epilepsy; amentia; and hypertonus. No treatment given. Patient discharged.

Dates: 1938