Correspondence is all in photocopied form, apart from original correspondence between F.A.E Crew and Charlotte Burghes (later Haldane) of the Science News Service concerning the submission of articles written by Crew. Most of the correspondence is from or to the International Education Board (a subsidiary of the Rockefeller Foundation, whose £30,000 grant in 1927 went towards the endowment of a Chair of Animal Genetics) and the Board of Agriculture for Scotland. Matters concern the administration and funding of the Department/Institute, and the establishment of the Imperial Bureau of Animal Genetics. Items of correspondence after the 1930s generally concern historical enquiries from various individuals about the Institute and its staff.

There is a gap in the material between 1935 and 1974.