Motor Neuron Disease
Subject
Subject Source: Medical Subject Headings
Scope Note: Notes = Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy ( BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089),Created For = LHSA-Dott
Found in 1 Collection or Record:
File regarding the application for HFEA license R0158-1-a for the project 'Derivation of human embryo stem cells by cell nuclear replacement technology development and the study of Motor Neuron disease', 2004-2005
File — Box CLX-A-1501: Series Coll-1320/2, Box: data_value_missing_7f052e8ef38e306c3aea1287509fa75d, Box: data_value_missing_ccc921af981a8bf28350e9fba593b2d1
Identifier: Coll-1320/2/5/3
Scope and Contents
Contains a copy of the application form and related correspondence, and a copy of the report of the inspection visit by the HFEA to Roslin Institute's Department of Gene Expression and Development on 2 November 2004.
Dates:
2004-2005